Understanding Sildenafil

When a man experiences sexual stimulation, nitric oxide is released into the penis, triggering the activation of the enzyme guanylate cyclase. This enzyme boosts levels of cyclic guanosine monophosphate (cGMP), which relaxes the smooth muscle in the penile arteries, allowing increased blood flow and resulting in an erection.

Sildenafil functions by inhibiting the PDE5 enzyme, which breaks down cGMP in the penis. By blocking PDE5, sildenafil helps maintain elevated cGMP levels, thereby extending the duration of an erection.

It's crucial to understand that Viagra does not initiate sexual arousal. Instead, it supports the body's natural physiological response to stimulation. Consulting a healthcare professional is recommended to ensure proper use and awareness of potential side effects